65 Powerful Bible Quotes to Anchor You When You Want to Give Up
It’s okay to be tired.
Let’s just start there, because it’s the one thing you probably haven’t let yourself feel. When the world is shouting hustle, and your own heart is whispering failure, it’s easy to believe that feeling exhausted is a sign of weakness. But it’s not. It’s a sign that you’ve been fighting hard. Whether you’re battling in your career, your relationships, your health, or even in your faith, the desire to just… stop… is profoundly human.
The beautiful thing is, the Bible doesn't shy away from this reality. It doesn’t promise a life free from storms, but it does promise an unbreakable anchor for the soul. The pages of scripture are filled with stories of people who were weary, afraid, and ready to quit-and the God who met them there with unlimited strength for the fight.
These bible quotes about not giving up aren’t just words; they are spiritual anchors. They are promises to hold onto when the waves of exhaustion and doubt threaten to carry you away. Here, you’ll find 65 verses categorized not just by theme, but by the specific feeling you might be facing right now-from burnout and shame to the long, quiet wait for a breakthrough.
Biblical perseverance isn't about gritting your teeth and powering through on your own. It’s about hupomonē-an active, hopeful endurance that comes from leaning on a power much, much greater than our own. Let’s find your anchor.
Anchor 1: Verses for Exhaustion and Burnout (When You Feel Too Tired to Try)
This is for the days when your energy is gone. When you’ve poured from an empty cup for far too long, and the thought of one more push feels impossible. This is where God’s strength shines brightest.
Renewing Your Strength When You Faint
God’s power isn’t just an additive; it’s a replacement. It works best right at the documented edge of our own weakness. When you have nothing left, He has everything you need.
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"But they who wait for the Lord shall renew their strength; they shall mount up with wings like eagles; they shall run and not be weary; they shall walk and not faint." - Isaiah 40:31, ESV
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"I can do all things through him who strengthens me." - Philippians 4:13, ESV
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"My grace is sufficient for you, for my power is made perfect in weakness. Therefore I will boast all the more gladly of my weaknesses, so that the power of Christ may rest upon me." - 2 Corinthians 12:9, ESV
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"Fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand." - Isaiah 41:10, ESV
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"God is our refuge and strength, a very present help in trouble." - Psalm 46:1, ESV
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"Wait for the Lord; be strong, and let your heart take courage; wait for the Lord!" - Psalm 27:14, ESV
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"Be strong and courageous. Do not be frightened, and do not be dismayed, for the Lord your God is with you wherever you go." - Joshua 1:9, ESV
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"The Lord will fight for you, and you have only to be silent." - Exodus 14:14, ESV
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"The joy of the Lord is your strength." - Nehemiah 8:10, ESV
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"Humble yourselves, therefore, under the mighty hand of God so that at the proper time he may exalt you, casting all your anxieties on him, because he cares for you." - 1 Peter 5:6-7, ESV
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"For God gave us a spirit not of fear but of power and love and self-control." - 2 Timothy 1:7, ESV
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"I lift up my eyes to the hills. From where does my help come? My help comes from the Lord, who made heaven and earth." - Psalm 121:1-2, ESV
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"He gives power to the faint, and to him who has no might he increases strength." - Isaiah 40:29, ESV
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"But the Lord is faithful. He will establish you and guard you against the evil one." - 2 Thessalonians 3:3, ESV
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"Though I walk in the midst of trouble, you preserve my life; you stretch out your hand against the wrath of my enemies, and your right hand delivers me." - Psalm 138:7, ESV
The Command to Not Grow Weary
Sometimes, we need more than a gentle comfort; we need a loving command. These verses are direct instructions from a God who knows our tendency to lose heart, especially when we’re focused on “doing good” and see no immediate results.
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"And let us not grow weary of doing good, for in due season we will reap, if we do not give up." - Galatians 6:9, ESV
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"As for you, brothers, do not grow weary in doing good." - 2 Thessalonians 3:13, ESV
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"If you faint in the day of adversity, your strength is small." - Proverbs 24:10, ESV
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"I know that you have perseverance and have endured for my name's sake, and have not grown weary." - Revelation 2:3, ESV
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"But the one who endures to the end will be saved." - Matthew 24:13, ESV
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"For we have come to share in Christ, if indeed we hold our original confidence firm to the end." - Hebrews 3:14, ESV
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"We are afflicted in every way, but not crushed; perplexed, but not driven to despair; persecuted, but not forsaken; struck down, but not destroyed." - 2 Corinthians 4:8-9, ESV
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"Even in laughter the heart may ache, and the end of joy may be grief." - Proverbs 14:13, ESV
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"Do not let your heart envy sinners, but continue at all times in the fear of the Lord. Surely there is a future, and your hope will not be cut off." - Proverbs 23:17-18, ESV
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"Therefore, my beloved brothers, be steadfast, immovable, always abounding in the work of the Lord, knowing that in the Lord your labor is not in vain." - 1 Corinthians 15:58, ESV
A Prayer for Spiritual Renewal and Energy
Lord, my spirit is tired and my body is weak. I feel like I’m running on empty. But your word in Isaiah 40:31 promises that if I wait for you, you will renew my strength. I choose to stop striving in my own power and wait on you right now. As Galatians 6:9 says, help me not to grow weary in doing good. Remind me that there is a harvest coming, even if I can’t see it yet. Lift me up on wings like eagles. Amen.
Anchor 2: Quotes for the Daily Grind (The Race of Endurance)
Once we’ve acknowledged our fatigue, we can activate our spiritual discipline. Life is often less of a sprint and more of a marathon. It requires painful endurance and a steady pace, with our eyes fixed firmly on the prize.
Running the Race Set Before Us
The Christian life is an active pursuit. These verses remind us to throw off the weight of distractions, regrets, and sins that slow us down and to run with purpose toward the finish line-Jesus himself.
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"Therefore, since we are surrounded by so great a cloud of witnesses, let us also lay aside every weight, and sin which clings so closely, and let us run with endurance the race that is set before us, looking to Jesus, the founder and perfecter of our faith." - Hebrews 12:1-2, ESV
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"Do you not know that in a race all the runners run, but only one receives the prize? So run that you may obtain it." - 1 Corinthians 9:24, ESV
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"I have fought the good fight, I have finished the race, I have kept the faith." - 2 Timothy 4:7, ESV
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"Not that I have already obtained this or am already perfect, but I press on to make it my own, because Christ Jesus has made me his own." - Philippians 3:12, ESV
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"Let us hold fast the confession of our hope without wavering, for he who promised is faithful." - Hebrews 10:23, ESV
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"And let steadfastness have its full effect, that you may be perfect and complete, lacking in nothing." - James 1:4, ESV
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"No one who puts his hand to the plow and looks back is fit for the kingdom of God." - Luke 9:62, ESV
Standing Firm and Unshaken
Endurance isn't always about moving forward; sometimes it’s about holding your ground. When temptations, accusations, and pressures try to push you over, these verses are your mandate to stand firm, rooted in your faith and protected by the armor of God. The daily grind often requires this kind of spiritual resilience, which is a theme you can explore in various quotes about resilience and healing.
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"Therefore take up the whole armor of God, that you may be able to withstand in the evil day, and having done all, to stand firm." - Ephesians 6:13, ESV
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"Be watchful, stand firm in the faith, act like men, be strong." - 1 Corinthians 16:13, ESV
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"Resist him, firm in your faith, knowing that the same kinds of suffering are being experienced by your brotherhood throughout the world." - 1 Peter 5:9, ESV
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"Submit yourselves therefore to God. Resist the devil, and he will flee from you." - James 4:7, ESV
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"For everyone who has been born of God overcomes the world. And this is the victory that has overcome the world-our faith." - 1 John 5:4, ESV
Anchor 3: Verses for Hope in Tribulation (Reframing Suffering)
It’s one thing to endure, but it’s another to find hope inside the hardship. Scripture doesn’t just tell us to survive suffering; it tells us that suffering has a purpose. It’s a tool God uses to refine our character, deepen our faith, and prepare us for something far greater.
When Affliction Seems Endless
These verses are a powerful reminder that our current pain is temporary and disproportionately small compared to the eternal reward it is producing in us.
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"Count it all joy, my brothers, when you meet trials of various kinds, for you know that the testing of your faith produces steadfastness." - James 1:2-3, ESV
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"And we know that for those who love God all things work together for good, for those who are called according to his purpose." - Romans 8:28, ESV
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"So we do not lose heart. Though our outer self is wasting away, yet our inner self is being renewed day by day. For this light momentary affliction is preparing for us an eternal weight of glory beyond all comparison." - 2 Corinthians 4:16-17, ESV
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"Rejoice in hope, be patient in tribulation, be constant in prayer." - Romans 12:12, ESV
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"Beloved, do not be surprised at the fiery trial when it comes upon you to test you, as though something strange were happening to you, but rejoice insofar as you share Christ's sufferings." - 1 Peter 4:12-13, ESV
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"In this you rejoice, though now for a little while, if necessary, you have been grieved by various trials, so that the tested genuineness of your faith-more precious than gold that perishes though it is tested by fire-may be found to result in praise and glory and honor at the revelation of Jesus Christ." - 1 Peter 1:6-7, ESV
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"May the God of hope fill you with all joy and peace in believing, so that by the power of the Holy Spirit you may abound in hope." - Romans 15:13, ESV
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"Many are the afflictions of the righteous, but the Lord delivers him out of them all." - Psalm 34:19, ESV
An Affirmation for Hard Times
When your mind is filled with doubt, speak truth to it. Based on Romans 8:28, repeat this to yourself: “I will not give up, because even this struggle is being worked by God for my ultimate good.”
The Assurance of God’s Presence
Perhaps the most powerful promise for someone in the midst of a trial is this: you are not alone. Feeling isolated is one of the enemy’s greatest tools, but God’s word repeatedly demolishes that lie.
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"Be strong and courageous. Do not fear or be in dread of them, for it is the Lord your God who goes with you. He will not leave you or forsake you." - Deuteronomy 31:6, ESV
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"Such hope does not put us to shame, because God’s love has been poured into our hearts through the Holy Spirit who has been given to us." - Romans 5:5, ESV
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"But the Lord stood by me and strengthened me, so that through me the message might be fully proclaimed and all the Gentiles might hear it. So I was rescued from the lion's mouth." - 2 Timothy 4:17, ESV
Anchor 4: Verses for Second Chances and Redemption (Overcoming Failure)
Sometimes the urge to give up doesn’t come from outside pressure, but from inside shame. We messed up. We failed. We dropped the ball. These moments can be the most discouraging of all, but they are also where God’s grace is most profound.
Leaving the Past Behind
God’s faithfulness is not dependent on our perfect performance. His mercies are new every single morning, giving you a fresh start no matter what yesterday held.
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"We are confident of this, that he who began a good work in you will carry it on to completion until the day of Christ Jesus." - Philippians 1:6, ESV
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"Fight the good fight of the faith. Take hold of the eternal life to which you were called." - 1 Timothy 6:12, ESV
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"But you, beloved, build yourselves up in your most holy faith, praying in the Holy Spirit, keep yourselves in the love of God, waiting for the mercy of our Lord Jesus Christ that leads to eternal life." - Jude 1:20-21, ESV
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"Take care that you are not carried away with the error of lawless people and lose your own stability. But grow in the grace and knowledge of our Lord and Savior Jesus Christ." - 2 Peter 3:17-18, ESV
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"He alone is my rock and my salvation, my fortress; I shall not be greatly shaken." - Psalm 62:2, ESV
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"No temptation has overtaken you that is not common to man. God is faithful, and he will not let you be tempted beyond your ability, but with the temptation he will also provide the way of escape, that you may be able to endure it." - 1 Corinthians 10:13, ESV
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"The Lord is my rock and my fortress and my deliverer, my God, my rock, in whom I take refuge, my shield, and the horn of my salvation, my stronghold." - Psalm 18:2, ESV
The Promise of the Crown: The Ultimate Motivation
When the finish line seems impossibly far, lift your eyes and remember what’s waiting there. The Bible doesn't promise a life without struggle, but it guarantees that for those who endure, the reward is infinitely greater than the trial.
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"I am coming soon. Hold fast what you have, so that no one may seize your crown." - Revelation 3:11, ESV
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"Blessed is the man who remains steadfast under trial, for when he has stood the test he will receive the crown of life, which God has promised to those who love him." - James 1:12, ESV
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"And you will be hated by all for my name's sake. But the one who endures to the end will be saved." - Matthew 10:22, ESV
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"For without faith it is impossible to please him, for whoever would draw near to God must believe that he exists and that he rewards those who seek him." - Hebrews 11:6, ESV
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"If we endure, we will also reign with him; if we deny him, he also will deny us." - 2 Timothy 2:12, ESV
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"No, in all these things we are more than conquerors through him who loved us. For I am sure that neither death nor life, nor angels nor rulers, nor things present nor things to come, nor powers, nor height nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord." - Romans 8:37-39, ESV
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"The one who conquers will inherit all things, and I will be his God and he will be my son." - Revelation 21:7, ESV
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"Therefore, brothers, be all the more diligent to confirm your calling and election, for if you practice these qualities you will never fall. For in this way there will be richly provided for you an entrance into the eternal kingdom of our Lord and Savior Jesus Christ." - 2 Peter 1:10-11, ESV
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"In that day you will know that I am in my Father, and you in me, and I in you." - John 14:20, ESV
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"Commit your way to the Lord; trust in him, and he will act." - Psalm 37:5, ESV
Practical Application: How to Use These Anchors Daily
Inspiration is wonderful, but it fades. Turning these verses into daily practice is how you build true faith endurance.
The Sentimentsource 3-Step Strategy for Resilience
- Select Your Verse: Don’t try to meditate on all 65. Choose one verse that speaks directly to your heart today. Write it down. Put it on your mirror. Make it your phone’s lock screen.
- Turn it into Prayer: Use our prayer prompt as a model. Speak the verse back to God and ask Him to make it true in your life. Personalize it. "Lord, you said you would be my strength. Today, I need that strength for my meeting at 2 PM."
- Repeat as Affirmation: When negative thoughts or feelings of defeat creep in, combat them by speaking your chosen verse out loud. Your voice has power, especially when it’s declaring God’s truth.
Nurturing the Habit of Endurance
Remember, even small, consistent acts of faith build immense spiritual muscle. This can include finding inspiration from volunteer work which puts our struggles into perspective, as discussed in posts on finding gratitude through volunteering. Most importantly, seek out community. Ecclesiastes 4:9-10 reminds us, “Two are better than one… for if they fall, one will lift up his fellow.” Don’t fight alone. And remember that spiritual rest is not quitting; it’s refueling.
Frequently Asked Questions
Q: What is a short Bible verse for when I feel like quitting?
A: A powerful and concise verse is Philippians 4:13: "I can do all things through him who strengthens me." It's a direct reminder that your ability to persevere doesn't come from you, but from the divine strength available to you in Christ.
Q: How does the Bible define perseverance?
A: The Bible often uses the Greek word hupomonē, which means more than just passive patience. It describes active, steadfast endurance and the ability to bear up under trials with hope and fortitude, trusting in God's ultimate purpose.
Q: What does the Bible say about burnout?
A: While the term "burnout" is modern, the concept is biblical. Verses like Isaiah 40:31 ("…they shall run and not be weary; they shall walk and not faint.") and Jesus' invitation in Matthew 11:28 ("Come to me, all who labor and are heavy laden, and I will give you rest.") directly address spiritual and physical exhaustion, offering divine rest as the solution.
You Are Not Fighting Alone
Feeling the urge to give up doesn’t mean your faith is weak. It means your trial is hard. But you are held, you are seen, and you are upheld by the righteous right hand of a God who never grows weary.
The race He has set before you is not a race you have to run in your own strength. So today, grab onto one of these anchors. Let it hold you steady. And just keep going, one prayer, one verse, one breath at a time. You’re closer to the harvest than you think.
[Share Your Anchor] - Which quote anchored your soul today? Share it in the comments below to encourage someone else who needs it